Polyclonal Antibody Production for Membrane Proteins via Genetic Immunization
نویسندگان
چکیده
منابع مشابه
Polyclonal Antibody Production for Membrane Proteins via Genetic Immunization.
Antibodies are essential for structural determinations and functional studies of membrane proteins, but antibody generation is limited by the availability of properly-folded and purified antigen. We describe the first application of genetic immunization to a structurally diverse set of membrane proteins to show that immunization of mice with DNA alone produced antibodies against 71% (n = 17) of...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep21925